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PolyAn

Micro- & Nanoparticles

PolyAn’s microparticles can be colour encoded with a wide range of fluorescent dyes and functionalized with PolyAn reactive 3D-matrices.
 

PolyAn is offering a portfolio of monodisperse PMMA (poly methyl methacrylate) particles for multiplex bead assays, calibration of flow cytometers and calibration of fluorescence imaging systems as well as a wide range of other applications in LifeScience research.
 
PolyAn’s microparticles can be colour encoded with up to six fluorescent dyes. The fluorophores are directly incorporated into the core of the bead during the microparticle formation. This ensures a much more homogeneous distribution of the dyes within the beads when compared to conventional diffusion controlled dyeing processes. Additionally, the fuorophores are caged within the polymeric PMMA matrix and thus less likely to leak-out. 
 
PolyAn’s microparticles are functionalized using our proprietary Molecular Surface Engineering (MSE) Technology. PolyAn’s reactive matrices are suitable as a platform for a wide range of coupling methods. Our microparticles are characterized by low non-specific adsorption and low aggregation behaviour.
 
Using PMMA ensures an excellent optical brilliance and a low autofluorescence compared to other microparticle materials. The refractive index of 1.48 is close to the refractive index of cells (ca. 1.38). Our microparticles have a density of 1.18 g/cm³ and a glass transition temperature (Tg) of about 110°C. PolyAn’s PMMA is biocompatible.
 
PolyAn produces microparticles in the range between 2-20µm. Each bead population is monodisperse with a maximum Coefficient of Variation (CV) of less than 5%.
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Features:

• PolyAn’s PMMA is biocompatible and without cytotoxicity

• Each bead population is monodisperse with CV < 5%

• Low non-specific adsorption and low aggregation surface

• PolyAn’s microparticles can be functionalized with PolyAn reactive 3D-matrices: 3D-Carboxy, 3D-Alkyne, 3D-Azide (click-chemistry), 3D-Aldehyde, Streptavidin, Neutravidin, Biotin, Protein A/G, Poly-L-Lysine, Oligonucleotides, Peptides, Antibodies
 

Applications：

• Flow Cytometry

• Multiplex Suspension Arrays

• Image based Multiplex Assays

• Fluorescence Standards

• (in vivo) Imaging

• Fluorescence Lifetime

• Fluid tracing and cell tracking

• Catalysis, Enzyme Immobilisation and Scavenger Materials
 

 

Multimedia

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PolyAn

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