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InnoQuant—基于激光共聚焦技术的4通道荧光组织切片&生物芯片扫描仪

• Innopsys 公司

成立于1999年,总部位于法国的图卢兹,并设立美国芝加哥分部

20多年专注于荧光检测硬件生产和软件自主开发,全球装机客户已超过600家

 

• InnoQuant 激光共聚焦组织切片&生物芯片扫描仪

 基于激光共聚焦原理与全玻片线性扫描技术

 快速完成组织切片/生物芯片的4色扫描,实现细胞、组织结构的定位、定性和定量分析

 
 

技术原理

 

产品特点

 

应用方向

 

典型案例

案例1 非小细胞肺癌切片多重染色

染料: nuclei – DAPI ; PDL1 – FITC;CD4 – AF594;Granzyme B  (NK cells) – Cy5

 

案例2 鼠肾切片双色标记

染料:血管:488;神经系统:633;切片厚度:550um

 

案例3 鼠脑矢状切片双色标记

染料:血管:488;多巴胺能神经元:633;切片厚度:550um

 

案例4 植物组织自发荧光扫描

百合花切片488/ 561/ 640自发荧光三色成像

 

案例5 小鼠脑片多色成像

染料:DAPI:蓝色; Lectin:绿色; Aquaporin 4 :红色

 

案例6 小鼠脑片多色成像

染料:DAPI:蓝色; GFAP:橙色; MBP:红色

 

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发表文献

2025年发表文献

1.Han, M.-M., et al., 8-Oxoguanine Modifications in Peripheral Leukocyte microRNAs Promote Age-related Inflammation by Remodeling Gene Regulatory Networks. 中国医学科学院老年医学研究所    Radical Biology and Medicine

2.Luo, J.-q., et al., Adipose stem cells ameliorate erectile dysfunction in diabetes mellitus rats by attenuating ferroptosis through NRP1 with SLC7A11 interaction. 南方医科大学南方医院   Radical Biology and Medicine

3.Li, J., et al., Comprehensive single-cell analysis deciphered the immunoregulatory mechanism of TPPU in alleviating sepsis-related acute liver injury. Journal of 郑州大学第一附属医院   Advanced Research

4.Zhao, Z., et al., Development and Validation of a Diagnostic Model for Stanford Type B Aortic Dissection Based on Proteomic Profiling. 河北医科大学第二医院   Journal of Inflammation Research

5.Li, Z., et al., Elevated LIF and JAK-STAT activation drive severe COVID-19 in myeloma patients receiving the BCMA-CD3 bispecific antibody Elranatamab. 中国医学科学院北京协和医院   Journal of Translational Medicine

6.Bi, Y., et al., Exosomal miR-302b rejuvenates aging mice by reversing the proliferative arrest of senescent cells. Cell Metabolism. 中国科学院生物物理研究所Cell Metabolism

7.Liao, Q., et al., Gut microbial metabolite 4-hydroxybenzeneacetic acid drives colorectal cancer progression via accumulation of immunosuppressive PMN-MDSCs. 南方医科大学基础医学院The Journal of Clinical Investigation

8.Hu, W., et al., Identification and Validation of Key Amino Acids in IgE Linear Epitopes of β-Lactoglobulin: Comparison of Recognition Patterns of Chinese Bovine Milk-Allergic Sera with Different Symptoms. 南昌大学   Journal of Agricultural and Food Chemistry, 

9.Liu, Y., et al., Isolation, structural characterization of natural chondroitin sulfate oligosaccharides and their binding study with anti-angiogenic factors. 西北大学   Carbohydrate Polymers

10.Zhang, X., et al., A machine learning-based prognostic signature utilizing MSC proteomics for predicting bladder cancer prognosis and treatment response.兰州大学    Translational Oncology


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