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产品中心

Pippin HT—整合脉冲场功能,全自动运行,高通量(24个样本),高精度;既可以筛选回收小片段DNA,也可以实现对几十kb的大片段更加精准的回收

• Sage Science 公司

位于美国马萨诸塞州,2010年成立,专注于核酸领域的样品制备

全球超过3000家客户的认可,国内装机数量400台左右

2万篇文献中应用,包括众多Nature、 Science、 Cell系列的文章

DNA片段筛选回收领域的行业金标准

 

• Pippin HT 全自动DNA脉冲场电泳回收仪

采用双通道电泳回收专利技术

一次最多运行24个样品,全自动运行

实现高精度回收、微量样品回收、高得率回收、大片段(几kb、几十kb甚至几百kb)回收、宽范围回收

实现对常规手工切胶和磁珠方法无法回收或回收不好的DNA样品筛选回收 

 

技术原理

 

产品特点

 

应用方向

 

典型案例

PacBio测序HiFi文库金标准,全新的Range+T模式可以更好的控制文库大小分布

Range+T模式,同一起始模板,同一回收起点,不同回收时间得到不同长度HiFi文库

 

     

       代表客户


 

 

发表文献

1.Porubsky, David, et al. "Human de novo mutation rates from a four-generation pedigree reference." Nature (2025): 1-10.

2.Jeong, Hyeonsoo, et al. "Structural polymorphism and diversity of human segmental duplications." Nature genetics 57.2 (2025): 390-401.

3.Park, Jimin, et al. "Accurate somatic small variant discovery for multiple sequencing technologies with DeepSomatic." Nature Biotechnology (2025): 1-10.

4.Mahmoud, Medhat, et al. "Utility of long-read sequencing for All of Us." Nature Communications 15.1 (2024): 837.

5.Healey, A. L., et al. "The complex polyploid genome architecture of sugarcane." Nature  (2024): 804-810.

6.Hwang, Sung-Yeon, et al. "Human cytomegalovirus harnesses host L1 retrotransposon for efficient replication." Nature Communications 15.1 (2024): 7640.

7.Chiang, Chi-Ling, et al. "Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer." Nature communications 14.1 (2023): 6692.

8.Sun, Yu H., et al. "Amniotes co-opt intrinsic genetic instability to protect germ-line genome integrity." Nature communications 14.1 (2023): 812.

9.Boers, Ruben, et al. "Retrospective analysis of enhancer activity and transcriptome history." Nature Biotechnology 41.11 (2023): 1582-1592.

10.Hallast, Pille, et al. "Assembly of 43 human Y chromosomes reveals extensive complexity and variation." Nature 621.7978 (2023): 355-364.


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